Murray Gell-Mann on Beauty and Truth

What is especially striking and remarkable is that in fundamental physics a beautiful or elegant theory is more likely to be right than a theory that is inelegant.
In 1957 some of us put forward a partially complete theory of the weak force, in disagreement with the results of seven experiments. It was beautiful and so we dared to publish it, believing that all those experiments must be wrong.

In fact, they were wrong.

From Newton:

This principle of nature being very remote from the conceptions of Philosophers, I forbore to describe it in that book, least I should be accounted an extravagant freak and so prejudice my Readers against all those things which were the main designe of the book.

TED link,
Marc Girod